node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MCON_0721 | MCON_1060 | MCON_0721 | MCON_1060 | Hypothetical protein | Hypothetical protein | 0.651 |
MCON_0721 | MCON_1545 | MCON_0721 | MCON_1545 | Hypothetical protein | Hypothetical protein | 0.599 |
MCON_0721 | MCON_1550 | MCON_0721 | MCON_1550 | Hypothetical protein | Hypothetical protein | 0.659 |
MCON_0721 | MCON_1952 | MCON_0721 | MCON_1952 | Hypothetical protein | Ser/Thr protein phosphatase family protein | 0.553 |
MCON_0721 | MCON_2842 | MCON_0721 | MCON_2842 | Hypothetical protein | OB-fold nucleic acid binding domain-containing protein | 0.645 |
MCON_0721 | cdc6 | MCON_0721 | MCON_1518 | Hypothetical protein | Cell division control protein 6; Involved in regulation of DNA replication | 0.577 |
MCON_0721 | endA | MCON_0721 | MCON_2907 | Hypothetical protein | tRNA-splicing endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5’ and 3’ splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2’,3’ cyclic phosphate and 5’-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp | 0.609 |
MCON_0721 | pcn | MCON_0721 | MCON_1510 | Hypothetical protein | DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication | 0.627 |
MCON_0721 | priL | MCON_0721 | MCON_1508 | Hypothetical protein | DNA primase, large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair | 0.599 |
MCON_0721 | priS | MCON_0721 | MCON_1623 | Hypothetical protein | DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...] | 0.629 |
MCON_0721 | rfcL | MCON_0721 | MCON_1488 | Hypothetical protein | Replication factor C large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA | 0.405 |
MCON_0721 | rpa | MCON_0721 | MCON_1551 | Hypothetical protein | Single-stranded DNA-binding replication protein A | 0.670 |
MCON_0721 | top6A | MCON_0721 | MCON_1547 | Hypothetical protein | DNA topoisomerase VI subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity | 0.463 |
MCON_0721 | topA | MCON_0721 | MCON_0764 | Hypothetical protein | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5’-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3’-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA super [...] | 0.440 |
MCON_1060 | MCON_0721 | MCON_1060 | MCON_0721 | Hypothetical protein | Hypothetical protein | 0.651 |
MCON_1060 | MCON_1545 | MCON_1060 | MCON_1545 | Hypothetical protein | Hypothetical protein | 0.631 |
MCON_1060 | MCON_1550 | MCON_1060 | MCON_1550 | Hypothetical protein | Hypothetical protein | 0.660 |
MCON_1060 | endA | MCON_1060 | MCON_2907 | Hypothetical protein | tRNA-splicing endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5’ and 3’ splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2’,3’ cyclic phosphate and 5’-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp | 0.477 |
MCON_1060 | pcn | MCON_1060 | MCON_1510 | Hypothetical protein | DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication | 0.619 |
MCON_1060 | priL | MCON_1060 | MCON_1508 | Hypothetical protein | DNA primase, large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair | 0.624 |