MCON_1550 protein (Methanosaeta concilii)

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Summary view: shows current interactions. Nodes can be moved; popups provide information on nodes & edges.

Databases

Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.

Experiments

Co-purification, co-crystallization, Yeast2Hybrid, Genetic Interactions, etc ... as imported from primary sources.

Textmining

Automated, unsupervised textmining - searching for proteins that are frequently mentioned together.

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Nodes and Egdes

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Network nodes represent host and virus proteins

Splice isoforms or post-translational modifications are collapsed, i.e. each host node represents all the proteins produced by a single, protein-coding gene locus. Virus nodes represent polyprotein cleavage products if the viral locus is polycistronic.

Edges represent protein-protein associations

Associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Your Input:

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[Homology]

Score

Proteins: MCON_1550

Predicted Functional Partners:

rpa

0.984

MCON_2842

0.851

MCON_1952

0.815

top6A

0.779

MCON_1545

0.774

top6B

0.752

MCON_1549

0.751

endA

0.671

MCON_1060

0.660

MCON_0721

0.659

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TSV: tab separated values - can be opened in Excel

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MCON_0721	MCON_1060	MCON_0721	MCON_1060	Hypothetical protein	Hypothetical protein	0.651
MCON_0721	MCON_1545	MCON_0721	MCON_1545	Hypothetical protein	Hypothetical protein	0.599
MCON_0721	MCON_1550	MCON_0721	MCON_1550	Hypothetical protein	Hypothetical protein	0.659
MCON_0721	MCON_1952	MCON_0721	MCON_1952	Hypothetical protein	Ser/Thr protein phosphatase family protein	0.553
MCON_0721	MCON_2842	MCON_0721	MCON_2842	Hypothetical protein	OB-fold nucleic acid binding domain-containing protein	0.645
MCON_0721	endA	MCON_0721	MCON_2907	Hypothetical protein	tRNA-splicing endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5’ and 3’ splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2’,3’ cyclic phosphate and 5’-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp	0.609
MCON_0721	rpa	MCON_0721	MCON_1551	Hypothetical protein	Single-stranded DNA-binding replication protein A	0.670
MCON_0721	top6A	MCON_0721	MCON_1547	Hypothetical protein	DNA topoisomerase VI subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity	0.463
MCON_1060	MCON_0721	MCON_1060	MCON_0721	Hypothetical protein	Hypothetical protein	0.651
MCON_1060	MCON_1545	MCON_1060	MCON_1545	Hypothetical protein	Hypothetical protein	0.631
MCON_1060	MCON_1550	MCON_1060	MCON_1550	Hypothetical protein	Hypothetical protein	0.660
MCON_1060	endA	MCON_1060	MCON_2907	Hypothetical protein	tRNA-splicing endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5’ and 3’ splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2’,3’ cyclic phosphate and 5’-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp	0.477
MCON_1060	rpa	MCON_1060	MCON_1551	Hypothetical protein	Single-stranded DNA-binding replication protein A	0.660
MCON_1060	top6A	MCON_1060	MCON_1547	Hypothetical protein	DNA topoisomerase VI subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity	0.446
MCON_1545	MCON_0721	MCON_1545	MCON_0721	Hypothetical protein	Hypothetical protein	0.599
MCON_1545	MCON_1060	MCON_1545	MCON_1060	Hypothetical protein	Hypothetical protein	0.631
MCON_1545	MCON_1549	MCON_1545	MCON_1549	Hypothetical protein	AsnC family transcriptional regulator	0.466
MCON_1545	MCON_1550	MCON_1545	MCON_1550	Hypothetical protein	Hypothetical protein	0.774
MCON_1545	endA	MCON_1545	MCON_2907	Hypothetical protein	tRNA-splicing endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5’ and 3’ splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2’,3’ cyclic phosphate and 5’-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp	0.546
MCON_1545	rpa	MCON_1545	MCON_1551	Hypothetical protein	Single-stranded DNA-binding replication protein A	0.775

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